Mrs. Takasato is the mother to Kaname and Suguru and wife to Mr. Takasato. She is very caring towards both her children, though Suguru seems to think she favours Kaname. She and Grandmother Takasato would get into arguments on how to discipline Kaname, which Mrs. Takasato would often lose.
While Mrs. Takasato is initially relieved when Kaname returns after being spirited away, the supernatural accidents that begin to occur around Kaname causes Mrs. Takasato to gradually fear and reject her older son, believing that he was switched with another child after disappearing. Kaname learns of his mother's true feelings when she refuses to attend the funeral of Mr. Ikuta, Kaname's art teacher, even at Suguru's insistence.